Genome Instability in Disease and Cancer (C7129)
Genome Instability in Disease and Cancer
Module C7129
Module details for 2025/26.
15 credits
FHEQ Level 6
Module Outline
Given how many cell divisions occur in an organisms’ lifetime it is remarkable that the genome remains so stable. This is largely thanks to highly conserved DNA repair processes which are vital for protection against cancer and other diseases. This module will explore the various types of DNA damage and a detailed mechanistic view of the repair processes that have evolved to repair such damage. Students will gain insights into the clinical consequences when these repair processes fail. This module will be taught by a mixture of lectures and interactive seminars exploring the key topics in more detail.
Module learning outcomes
Systematically research and write concisely about the various types and sources of DNA damage, how they link to mutagenesis and cancer, and their cognate repair processes.
Develop a working knowledge of the wide-ranging clinical phenotypes that result from defective DNA repair processesand the complexities associated with diagnosis of these disorders.
Develop skills in interpretation and critical evaluation of experimental research findings.
| Type | Timing | Weighting |
|---|---|---|
| Computer Based Exam | Semester 2 Assessment | 50.00% |
| Coursework | 50.00% | |
| Coursework components. Weighted as shown below. | ||
| Test | T2 Week 10 (1 hour 30 minutes) | 100.00% |
Timing
Submission deadlines may vary for different types of assignment/groups of students.
Weighting
Coursework components (if listed) total 100% of the overall coursework weighting value.
| Term | Method | Duration | Week pattern |
|---|---|---|---|
| Spring Semester | Seminar | 1 hour | 00100010010 |
| Spring Semester | Lecture | 1 hour | 22222222222 |
How to read the week pattern
The numbers indicate the weeks of the term and how many events take place each week.
Dr Alessandro Bianchi
Assess convenor
/profiles/215271
Dr Owen Wells
Assess convenor, Convenor
/profiles/260574
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