Introduction to Met & Pharmacology (C7135)
Introduction to Metabolism and Pharmacology
Module C7135
Module details for 2022/23.
15 credits
FHEQ Level 4
Module Outline
This 15 credit module aims to introduce the general principles of metabolism and pharmacology. The initial lectures cover ATP, substrate-level phosphorylation, Chemiosmosis and oxidative phosphorylation, glycolysis, and the the Krebs cycle. This is complemented by lectures covering glycogen, nucleotide and lipid metabolism, introducing metabolic flux with exercise as an example. Anti-metabolites, anti-cancer drugs and G protein agonist and antagonists will be discussed as examples of therapeutic intervention. The pharmacology aspects of the module will cover how drugs act at receptors, ion channels and specific enzymes, their molecular targets and the underlying cellular mechanisms of action. It will cover methods and measurement in pharmacology and the absorption and distribution of drugs, their elimination and pharmacokinetics.
Module learning outcomes
Demonstrate an understanding the major pathways of glucose metabolism and the general principles of metabolism including: metabolic regulation and energy coupling; energy coupling involving adenosine triphosphate (ATP); phosphate group transfer; substrate level phosphorylation (in glycolysis) and oxidative phosphorylation.
Demonstrate an understanding of: the Chemiosmotic theory; glycogen metabolism and its regulation; lipid metabolism and its regulation, including acute and long term exercise.
Demonstrate an understanding of nucleotide metabolism and anti-cancer drugs.
Demonstrate an understanding of: the general principles by which drugs act and measurement methods used in pharmacology; Phase 1 and Phase 2 drug metabolism and pharmacokinetics; the cellular mechanisms of drug action with reference to specific classes of drugs in routine use.
| Type | Timing | Weighting |
|---|---|---|
| Coursework | 40.00% | |
| Coursework components. Weighted as shown below. | ||
| Problem Set | T2 Week 9 | 50.00% |
| Test | T2 Week 11 (1 hour) | 50.00% |
| Multiple Choice questions | Semester 2 Assessment | 60.00% |
Timing
Submission deadlines may vary for different types of assignment/groups of students.
Weighting
Coursework components (if listed) total 100% of the overall coursework weighting value.
| Term | Method | Duration | Week pattern |
|---|---|---|---|
| Spring Semester | Lecture | 1 hour | 33333333333 |
How to read the week pattern
The numbers indicate the weeks of the term and how many events take place each week.
Dr Haruko Okamoto
Assess convenor, Convenor
/profiles/460041
Please note that the University will use all reasonable endeavours to deliver courses and modules in accordance with the descriptions set out here. However, the University keeps its courses and modules under review with the aim of enhancing quality. Some changes may therefore be made to the form or content of courses or modules shown as part of the normal process of curriculum management.
The University reserves the right to make changes to the contents or methods of delivery of, or to discontinue, merge or combine modules, if such action is reasonably considered necessary by the University. If there are not sufficient student numbers to make a module viable, the University reserves the right to cancel such a module. If the University withdraws or discontinues a module, it will use its reasonable endeavours to provide a suitable alternative module.