Cell Regulation and Cancer (C7108)
Cell Regulation and Cancer
Module C7108
Module details for 2022/23.
15 credits
FHEQ Level 5
Module Outline
The module aims to introduce students to the mechanisms by which cell metabolism and growth is regulated in normal and diseased states, focussing on cancer. It will cover cell regulation at the level of single cells and the body as a whole and will discuss the major signal transduction pathways used by hormones, neurotransmitters and growth factors to control cell growth and metabolism in the normal state and also the use of pharmacological agents to discriminate between receptor subtypes. This will lead to a discussion of how loss of control of these signaling pathways by the generation of oncogenes or changes in tumour suppressor genes leads to alterations in the cell cycle and the development of cancer. The difference between normal and transformed cells, the altered signal transduction mechanisms and the epidemiology, incidence and mortality in different cancers are reviewed.
Module learning outcomes
Demonstratean in depth knowledge of the molecular mechanisms by which metabolic pathways can be controlled via intracellular and extracellular homeostatic mechanisms using muscle contraction and glycogen metabolism as examples
Summarise the major signalling pathways by which hormones and other effectors elicit an intracellular response
Show an appreciation of the characteristics of normal and transformed cells
Critically discuss the concept of growth control and how its loss results in the development of cancer
| Type | Timing | Weighting |
|---|---|---|
| Coursework | 30.00% | |
| Coursework components. Weighted as shown below. | ||
| Test | T1 Week 11 (40 minutes) | 50.00% |
| Test | T1 Week 7 (40 minutes) | 50.00% |
| Computer Based Exam | Semester 1 Assessment | 70.00% |
Timing
Submission deadlines may vary for different types of assignment/groups of students.
Weighting
Coursework components (if listed) total 100% of the overall coursework weighting value.
| Term | Method | Duration | Week pattern |
|---|---|---|---|
| Autumn Semester | Lecture | 1 hour | 22222222222 |
How to read the week pattern
The numbers indicate the weeks of the term and how many events take place each week.
Miss Amy Horwood
Assess convenor
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Dr Joanna Richardson
Assess convenor, Convenor
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