Structural Basis of Biological Function (C7114)
Structural Basis of Biological Function
Module C7114
Module details for 2022/23.
15 credits
FHEQ Level 5
Module Outline
The module begins with the principles of protein architecture and the evolution of protein families. It then covers the properties of membrane proteins and the structural basis for generation of the protonmotive force in photosynthesis and respiration. How proteins use energy to achieve mechanical motion in 'molecular motors' is introduced. This is followed by discussion of protein folding and misfolding, and the roles of molecular chaperones. Post-translational modifications of proteins and their roles in signaling and regulation are described. Finally, we discuss how proteins interact with the other main biological polymers, the nucleic acids.
Module learning outcomes
Demonstrte an in depth understanding of the principles of protein architecture and the evolution of protein families.
Demonstrate a critical understanding of the role of protein structure in controlling protein function.
Describe the mechanism of protein folding, the role of post-translational modifications and the structure of molecular chaperones and motors.
Demonstrate a knowledge of the acquisition of relevant quantitative laboratory results and process and the evaluation of data with appropriate graphical tools.
| Type | Timing | Weighting |
|---|---|---|
| Coursework | 30.00% | |
| Coursework components. Weighted as shown below. | ||
| Report | T1 Week 9 | 60.00% |
| Computer Based Exam | T1 Week 9 | 40.00% |
| Computer Based Exam | Semester 1 Assessment | 70.00% |
Timing
Submission deadlines may vary for different types of assignment/groups of students.
Weighting
Coursework components (if listed) total 100% of the overall coursework weighting value.
| Term | Method | Duration | Week pattern |
|---|---|---|---|
| Autumn Semester | Laboratory | 3 hours | 00010100000 |
| Autumn Semester | Post Lab | 1 hour | 00000010001 |
| Autumn Semester | Pre Lab | 1 hour | 00010100000 |
| Autumn Semester | Workshop | 2 hours | 00000000100 |
| Autumn Semester | Lecture | 1 hour | 22202022222 |
How to read the week pattern
The numbers indicate the weeks of the term and how many events take place each week.
Prof Erika Mancini
Convenor, Assess convenor
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Dr Antony Oliver
Assess convenor
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Mrs Megan Wagstaff
Assess convenor
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Dr Chrisostomos Prodromou
Assess convenor
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