Regulating Gene Expression (C7132)
Regulating Gene Expression
Module C7132
Module details for 2023/24.
15 credits
FHEQ Level 6
Module Outline
This module takes a current perspective of the molecular mechanisms controlling RNA expression in eukaryotes, focusing largely on gene transcription and translation but also RNA processing and regulation by non-coding RNAs. We will explore how eukaryotic transcriptional regulators control RNA polymerase recruitment and retention and modulate chromatin structure during transcriptional activation and repression. The module will also focus on mechanisms of post-transcriptional gene control and protein translation. Understanding these processes and mechanisms is fundamental for our understanding of the regulation of normal cell growth and how it can become deregulated in diseases including cancer.
Module learning outcomes
Develop a systematic understanding of the fundamental principles and advanced concepts in gene expression regulation and non-coding RNA activity, integrating coherent and detailed knowledge from the forefront of current research in the field.
Acquire proficiency in deploying accurately established techniques of analysis and inquiry within the discipline of gene expression regulation, demonstrating the ability to critically assess research methodologies and experimental approaches.
Develop a deep conceptual understanding that enables to formulate sophisticated arguments, solve complex problems, and engage in advanced discussion using cutting-edge ideas and techniques from the discipline of regulating gene expression.
Enhance the ability to autonomously employ effective strategies to understand and contextualise peer-reviewed research articles and review articles. Develop the skills to critically evaluate and synthesise information from diverse sources, including original materials pertinent to this discipline
| Type | Timing | Weighting |
|---|---|---|
| Computer Based Exam | Semester 1 Assessment | 70.00% |
| Coursework | 30.00% | |
| Coursework components. Equal weighting for all components. | ||
| Essay | T1 Week 11 | |
Timing
Submission deadlines may vary for different types of assignment/groups of students.
Weighting
Coursework components (if listed) total 100% of the overall coursework weighting value.
| Term | Method | Duration | Week pattern |
|---|---|---|---|
| Autumn Semester | Lecture | 1 hour | 22222222222 |
| Autumn Semester | Seminar | 2 hours | 00100100100 |
How to read the week pattern
The numbers indicate the weeks of the term and how many events take place each week.
Prof Michelle West
Assess convenor
/profiles/116026
Dr Leandro Castellano
Assess convenor, Convenor
/profiles/437664
Dr Benjamin Towler
Assess convenor
/profiles/247980
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